Growth hormone pulse intensity can be increased through 4 possible mechanisms:

  1. Increasing GHRH (growth hormone releasing hormone) release.
  2. Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
  3. Reducing somatostatin release (somatostatin turns off GH release).
  4. Inhibiting of somatostatin receptor signaling.

Ibutamoren (MK-677) was found to work through all four of these mechanisms. After ingestion, Human Growth Hormone (hGH) was shown to increase dose dependently, meaning, that the higher the dose of Ibutamoren (MK-677) elicited a higher hGH release within the body. Clinical research trails have used doses starting at as little as 5mg/day, with the most efficient dose being 25mg/day.

Human Growth Hormone and the Ibutamoren (MK-677) connection

Human Growth Hormone (hGH) has been a hot topic for the last several years. Its ability to turn back your body’s internal clock, help you rapidly build lean muscle, burn stubborn body fat, increase libido, and improve your skin’s elasticity and appearance, all while elevating energy and vitality levels exponentially.

Famous actors, athletes, and anyone wanting to improve their current health and appearance have been looking at hGH therapy for years. hGH injections can be costly, inconvenient and painful, and you also need a prescription which is another barrier to entry.

In hGH discussions, there are often more questions than answers. Check out our straightforward Q&A, and learn how you can boost your own natural levels of this powerful anabolic and healing hormone.


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